Other substances

Withanolide A

A plant steroid lactone.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Natural product

1
 Supporting references
0
 Contradictory references
2
 AI-suggested references
0
 Clinical trials

General information

Withanolide A on PubChem

 

Structure image - Withanolide A

CC1=C(C(=O)O[C@H](C1)[C@@](C)([C@H]2CC[C@@H]3[C@@]2(CC[C@H]4[C@H]3[C@H]5[C@H](O5)[C@@]6([C@@]4(C(=O)C=CC6)C)O)C)O)C

Supporting references

Link Tested on Impact factor Notes Publication date
Traditional medicinal plants against replication, maturation and transmission targets of SARS-CoV-2: computational investigation
Spike protein ACE2 Small molecule In silico 		in silico 3.22

Predicted to bind the SARS-CoV-2 spike protein and the host ACE2 receptor.

 Nov/05/2020

AI-suggested references

Link Publication date
Structure-based virtual screening and molecular dynamics of phytochemicals derived from Saudi medicinal plants to identify potential COVID-19 therapeutics.
Aug/09/2020
Identification of novel inhibitors of SARS-CoV-2 main protease (Mpro) from Withania sp. by molecular docking and molecular dynamics simulation
Jul/20/2021
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