Other substances

Vinorelbine

A mitosis inhibitor, microtubule inhibitor and apoptosis inducer.

Phase of research

Potential treatment - theoretical effect

How it helps

Other treatment

Drug status

Used to treat other disease

1
 Supporting references
0
 Contradictory references
1
 AI-suggested references
0
 Clinical trials

General information

Vinorelbine is a chemotherapeutic targeting mitosis used for treatment of various malignancies (DrugBank).

Vinorelbine on PubChem
Vinorelbine on Wikipedia

Marketed as

BENDARELBIN; EBERELBIN; EUNEXON; EUROVINORELBIN; FILCRIN; NAVELBIN; NAVILDEZ; NAVIN; NAVIREL; NEOCITEC; NAVELBINE; RENOVEL; RIBORELBIN; VILNE; VINELBINE; VINORAYNE; VINOREL; VINORGEN; VINOTEL; VINORELBINE TARTRATE; ZINAVIN

 

Structure image - Vinorelbine

CCC1=C[C@H]2C[C@@](C3=C(CN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC

Supporting references

Link Tested on Impact factor Notes Publication date
Glucocorticoids improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels
in silico 4.86

In silico screening of potential ACE2 agonists. Theoretical amelioration of ACE2 depletion by virus attachment.

 Jun/27/2020

AI-suggested references

Link Publication date
Metronomic oral vinorelbine and lung cancer therapy during the COVID 19 pandemic: A single-center experience
Dec/01/2021
Export (.csv)