Other substances

Trimeprazine

An antipruritic phenothiazine.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Used to treat other disease

1
 Supporting references
0
 Contradictory references
0
 AI-suggested references
0
 Clinical trials

General information

Trimeprazine on DrugBank
Trimeprazine on PubChem
Trimeprazine on Wikipedia

Synonyms

Alimemazine

Marketed as

ALIMEZINE; NEDELTRAN; PANECTYL; REPELTIN; THERALEN; THERALENE; VALLERGAN

 

Structure image - Trimeprazine

CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)CN(C)C

Supporting references

Link Tested on Impact factor Notes Publication date
Identification of SARS-CoV-2 entry inhibitors among already approved drugs
Small molecule In vitro Screening 		Huh-7 cells (pseudovirus-based assay); Vero E6 cells (antiviral activity); SARS-CoV-2 (WIV04) 5.06

Inhibits SARS-CoV-2 spike protein pseudovirus cell entry and significally inhibits viral replication in vitro.

 Oct/28/2020
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