Other substances

Triclabendazole

An antihelminthic drug.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Used to treat other disease

1
 Supporting references
0
 Contradictory references
1
 AI-suggested references
0
 Clinical trials

General information

Triclabendazole is used for the treatment of fascioliasis in humans (DrugBank).

Triclabendazole on DrugBank
Triclabendazole on PubChem
Triclabendazole on Wikipedia

Marketed as

EGATEN; FASINEX

 

Structure image - Triclabendazole

CSC1=NC2=CC(=C(C=C2N1)Cl)OC3=C(C(=CC=C3)Cl)Cl

Supporting references

Link Tested on Impact factor Notes Publication date
Repurposing Low-Molecular-Weight Drugs against the Main Protease of Severe Acute Respiratory Syndrome Coronavirus 2
Small molecule Enzyme assay Screening 		in vitro 6.71

Inhibits SARS-CoV-2 3C-like protease in vitro.

 Jul/28/2020

AI-suggested references

Link Publication date
Zinc supplementation augments the suppressive effects of repurposed NF-kappaB inhibitors on ACE2 expression in human lung cell lines
Jun/23/2021
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