Other substances

TPNT1

A nanoparticle composite.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Experimental

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 Supporting references
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 Contradictory references
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 AI-suggested references
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 Clinical trials

General information

TPNT1 is a nanoparticle formulation displaying antiviral activity in cell-based assays. It contains chlorine dioxide, zinc oxide, silver, and gold nanoparticles (Chang et al., 2021).

 

Supporting references

Link Tested on Impact factor Notes Publication date
Nanoparticle composite TPNT1 is effective against SARS-CoV-2 and influenza viruses
In vitro Mixed substance 		in vitro binding assay; Vero E6 cells; H1975-ACE2 cells; HEK293T cells; SARS-CoV-2 strain SARS-CoV-2/NTU01/TWN/human/2020 4.00

The nanoparticle formulation inhibited SARS-CoV-2 infection with an SI of >10 in vitro.  It was shown to inhibit Spike-ACE2 binding. It was also observed to inhibit viral infection-associated syncytia formation.

 Apr/22/2021
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