Other substances

Thymoquinone

A bioactive quinone.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Natural product

Supporting references

Contradictory references

AI-suggested references

Clinical trials

General information

Thymoquinone on PubChem

Structure image - Thymoquinone

CC1=CC(=O)C(=CC1=O)C(C)C

Supporting references

Link	Tested on	Impact factor	Notes	Publication date
Deciphering underlying mechanism of Sars-CoV-2 infection in humans and revealing the therapeutic potential of bioactive constituents from Nigella sativa to combat COVID19: in-silico study ACE2 Small molecule In silico	in silico	3.22	Predicted to bind the host ACE2 receptor.	Oct/28/2020

AI-suggested references

Link	Publication date
Potential Implications of Black Seed and its Principal Constituent Thymoquinone in the Treatment of COVID-19 Patients.	Nov/13/2020
Inhibitory effect of thymoquinone from Nigella sativa against SARS-CoV-2 main protease. An in-silico study.	Apr/15/2022
In Silico Investigation of the SARS CoV2 Protease with Thymoquinone, the Major Constituent of Nigella Sativa.	Jul/13/2020
Effect of Thymoquinone on Acute Kidney Injury Induced by Sepsis in BALB/c Mice	Oct/06/2021
Computational and Experimental Studies Reveal That Thymoquinone Blocks the Entry of Coronaviruses Into In Vitro Cells	May/20/2021
Potential benefits of combination of Nigella sativa and Zn supplements to treat COVID-19.	Jun/24/2020
In silico analysis of quranic and prophetic medicinals plants for the treatment of infectious viral diseases including corona virus	Feb/23/2021
Identification of phytochemical inhibitors of SARS-CoV-2 protease 3CLpro from selected medicinal plants as per molecular docking, bond energies and amino acid binding energies	Mar/24/2022
Possible therapeutic effects of Nigella sativa and its thymoquinone on COVID-19	Feb/07/2022
Natural products may interfere with SARS-CoV-2 attachment to the host cell	Oct/29/2021
Computational approach towards the design of artemisinin-thymoquinone hybrids against main protease of SARS-COV-2.	Sep/06/2021
In vitro potential antiviral SARS-CoV-19- activity of natural product thymohydroquinone and dithymoquinone from Nigella sativa.	Jan/01/2022
The potential role of thymoquinone in preventing the cardiovascular complications of COVID-19.	Jul/23/2021
A molecular dynamics simulation study of the ACE2 receptor with screened natural inhibitors to identify novel drug candidate against COVID-19.	Apr/23/2021
Thymoquinone: A Promising Natural Compound with Potential Benefits for COVID-19 Prevention and Cure	May/03/2021
Alkaloids and flavonoids from African phytochemicals as potential inhibitors of SARS-Cov-2 RNA-dependent RNA polymerase: an in silico perspective	Jan/13/2022
Novel Thymoquinone Nanoparticles Using Poly(ester amide) Based on L-Arginine-Targeting Pulmonary Drug Delivery	Nov/13/2020