Teniposide

A DNA synthesis inhibitor.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Experimental

3
Supporting references
0
Contradictory references
2
AI-suggested references
0
Clinical trials

General information

Teniposide on PubChem

 

Structure image - Teniposide

COC1=CC(=CC(=C1O)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@@H](C4=CC5=C(C=C24)OCO5)O[C@H]6[C@@H]([C@H]([C@H]7[C@H](O6)CO[C@H](O7)C8=CC=CS8)O)O


Supporting references

Link Tested on Impact factor Notes Publication date
Repurposing approved drugs as potential inhibitors of 3CL-protease of SARS-CoV-2: Virtual screening and structure based drug design
3CLpro Small molecule In silico Screening
in silico 1.85

Predicted to inhibit SARS-CoV-2 3C-like protease.

Jul/31/2020
SARS-CoV-2 Mpro inhibitors: identification of anti-SARS-CoV-2 Mpro compounds from FDA approved drugs
3CLpro Small molecule In silico
in silico 3.22

Predicted to inhibit the SARS-CoV-2 3C-like protease.

Nov/05/2020
Bioinformatics and machine learning approach identifies potential drug targets and pathways in COVID-19
Small molecule In silico
in silico 8.99

Computational modelling predicts that the drug interacts with SARS-CoV-2 infection-related signalling pathways.

Apr/12/2021

AI-suggested references