Teicoplanin

A lipoglycopeptide antibiotic.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Experimental

Supporting references

Contradictory references

AI-suggested references

Clinical trials

Teicoplanin is a glycopeptide antibiotic complex with inhibitory activity on peptidoglycan polymerization (NCIt).

Teicoplanin on DrugBank
Teicoplanin on PubChem
Teicoplanin on Wikipedia

Link	Tested on	Impact factor	Notes	Publication date
Teicoplanin potently blocks the cell entry of 2019-nCoV Preprint	cell cultures			Feb/13/2020
Screening and evaluation of approved drugs as inhibitors of main protease of SARS-CoV-2 Biophysical assay Small molecule Enzyme assay In vitro	in vitro enzyme assay; in vitro biophysical assay	5.16	Manifests potent inhibition of the SARS-CoV-2 3C-like protease in vitro.	Aug/24/2020

Link	Publication date
Teicoplanin-A New Use for an Old Drug in the COVID-19 Era?	Nov/26/2021
In Vitro Data of Current Therapies for SARS-CoV-2.	Jun/24/2020
Targeting SARS-CoV-2 main protease by teicoplanin: A mechanistic insight by docking, MM/GBSA and molecular dynamics simulation.	Jul/18/2021
Drug Repurposing Approach, Potential Drugs, and Novel Drug Targets for COVID-19 Treatment	Jun/13/2020
Current status and strategic possibilities on potential use of combinational drug therapy against COVID-19 caused by SARS-CoV-2.	Jun/03/2020
Can treatment with teicoplanin improve the prognosis of COVID-19 patients?	Sep/18/2021
The role of teicoplanin in the treatment of SARS-CoV-2 infection: A retrospective study in critically ill COVID-19 patients (Tei-COVID study)	Dec/18/2020
Elucidation of Teicoplanin Interactions with Drug Targets Related to COVID-19.	Jul/15/2021
Old and re-purposed drugs for the treatment of COVID-19	Jun/01/2020
Pharmacological Modulators of Autophagy as a Potential Strategy for the Treatment of COVID-19.	Apr/15/2021
Teicoplanin: an alternative drug for the treatment of COVID-19?	Mar/13/2020
Natural Apocarotenoids and Their Synthetic Glycopeptide Conjugates Inhibit SARS-CoV-2 Replication	Oct/30/2021
Glycopeptide Antibiotic Teicoplanin Inhibits Cell Entry of SARS-CoV-2 by Suppressing the Proteolytic Activity of Cathepsin L	Apr/28/2022