Other substances

SYN_15517940

A protease inhibitor.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Experimental

1
 Supporting references
0
 Contradictory references
0
 AI-suggested references
0
 Clinical trials

General information

SYN_15517940 is a putative SARS-CoV-2 Papain-like protease inhibitor (Alamri et al., 2020).

Synonyms

((R)-2-methyl-6-(((1R,5R)-8-oxo-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(4H)-yl)sulfonyl)-2H-benzo[b][1,4]oxazin-3(4H)-one)

 

[H][C@@]35CN(S(=O)(=O)c2ccc1OC(C)C(=O)Nc1c2)C[C@@]([H])(C3)c4cccc(=O)n4C5

Supporting references

Link Tested on Impact factor Notes Publication date
Discovery of human coronaviruses pan-papain-like protease inhibitors using computational approaches
PapainLpro Small molecule In silico 		in silico 2.67

Predicted to inhibit the SARS-CoV-2 Papain-like protease. 

 Aug/28/2020
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