Potential treatment - theoretical effect
Taxifolin is a natural flavonoid from the polyphenols class. It can be found in various conifers, fruit, vegetables, wine, tea and cocoa. It is a potential chemoprotective agent. Taxifolin showed promising pharmacological activities in the management of inflammation, tumors, microbial infections, oxidative stress, cardiovascular, and liver disorders.
Regarding SARS-CoV-2, our AIM tool found the data that taxifolin could help against SARS-CoV-2 by inhibiting its protease.
(-)-Taxifolin (enantiomer); (+)-Taxifolin (enantiomer); dihydroquercetin
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Computational guided identification of a citrus flavonoid as potential inhibitor of SARS-CoV-2 main protease
small molecule in silico 3CLpro
(+)-Taxifolin is predicted to inhibit the SARS-CoV-2 3C-like protease.
Inhibitors for Novel Coronavirus Protease Identified by Virtual Screening of 687 Million Compounds
(-)-Taxifolin enantiomer. Inhibitors for Novel Coronavirus Protease Identified by Virtual Screening of 687 Million Compounds
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|NCT04871802||Effect of the Dietary Supplement Taxifolin Aqua on the Recovery Period After COVID-19 Pneumonia||Not yet recruiting||Not Applicable||May/10/2021||Oct/01/2021|