Statin (general)

A HMG-CoA reductase inhibitor class.

Phase of research

Potential treatment - clinical evidence

How it helps

Antiviral

Drug status

Used to treat other disease

1
Supporting references
0
Contradictory references
30
AI-suggested references
0
Clinical trials

General information

Statins are a class of cholesterol synthesis (HMG-CoA reductase) inhibitors with additional pleiotropic effects (Liao and Laufs, 2005).

Statins on Wikipedia

 


Supporting references

Link Tested on Impact factor Notes Publication date
Statin Use Is Associated with Decreased Risk of Invasive Mechanical Ventilation in COVID-19 Patients: A Preliminary Study
Small molecule Cohort study
Patients 3.02

Statin use (as a chronic medication) was associated with significantly lower invasive mechanical ventilation need. Difference between statin users and non-users in in-hospital death and ICU admission were insignificant, however. Sample size: 123 + 126 (no statin use).

Sep/17/2020

AI-suggested references

Link Publication date
Atorvastatin versus placebo in patients with covid-19 in intensive care: randomized controlled trial.
Jan/07/2022
Cost-effectiveness analysis of statins for the treatment of hospitalized COVID-19 patients.
Jan/06/2022
Association Between Statin Use Prior to Admission and Lower Coronavirus Disease 2019 (COVID-19) Severity in Patients With Cardiovascular Disease or Risk Factors.
Apr/29/2021
The association of statins use with survival of patients with COVID-19.
Sep/03/2021
Statins and Covid-19: The Neglected Front of bidirectional effects.
Feb/05/2021
Preadmission Statin Therapy and Clinical Outcome in Hospitalized Patients With COVID-19: An Italian Multicenter Observational Study
Jun/06/2020
Statins and clinical outcomes in hospitalized COVID-19 patients with and without Diabetes Mellitus: a retrospective cohort study with propensity score matching
Feb/17/2022
Central blood pressure lowering effect of telmisartan-rosuvastatin single-pill combination in hypertensive patients combined with dyslipidemia: A pilot study
Oct/18/2021
Icosapent Ethyl - A Successful Treatment for Symptomatic COVID-19 Infection
Sep/02/2020
Association between antecedent statin use and decreased mortality in hospitalized patients with COVID-19
Mar/08/2021
Statin therapy did not improve the in-hospital outcome of coronavirus disease 2019 (COVID-19) infection.
Aug/26/2020
Relation of Statin Use Prior to Admission to Severity and Recovery Among COVID-19 Inpatients.
Sep/16/2020
Statins in patients with COVID-19: a retrospective cohort study in Iranian COVID-19 patients.
Jan/25/2021
Association between antecedent statin use and severe disease outcomes in COVID-19: A retrospective study with propensity score matching.
Mar/06/2021
Association of Statins and 28-Day Mortality in Patients Hospitalized with SARS CoV-2 Infection
Mar/09/2020
Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit: The INSPIRATION Randomized Clinic
Mar/18/2021
Computational prediction of the molecular mechanism of statin group of drugs against SARS-CoV-2 pathogenesis
Apr/14/2022
Fluvastatin mitigates SARS-CoV-2 infection in human lung cells
Nov/18/2021
Discontinuation of atorvastatin use in hospital is associated with increased risk of mortality in COVID-19 patients
Nov/29/2021
Efficacy of Statin Therapy in Patients with Hospital Admission for COVID-19
Jun/18/2020
Icosapent Ethyl (Vascepa ) for the Treatment of Acute, Severe Pancreatitis.
May/15/2020
Statin Use in COVID-19 Hospitalized Patients and Outcomes: A Retrospective Study
Feb/24/2022
Identifying FDA-approved drugs with multimodal properties against COVID-19 using a data-driven approach and a lung organoid model of SARS-CoV-2 entry.
Sep/09/2021
Statin Use and In-hospital Mortality in Patients with COVID-19 and Coronary Heart Disease
Dec/13/2021
Prior Treatment with Statins is Associated with Improved Outcomes of Patients with COVID-19: Data from the SEMI-COVID-19 Registry
Mar/31/2022
Protective effect of Rosuvastatin on Azithromycin induced cardiotoxicity in a rat model
Mar/04/2022
Association of Statin Use With the In-Hospital Outcomes of 2019-Coronavirus Disease Patients: A Retrospective Study
Nov/17/2020
EFFECT OF STATIN THERAPY ON SARS-CoV-2 INFECTION-RELATED MORTALITY IN HOSPITALIZED PATIENTS
Mar/11/2020
Statin Use and In-Hospital Mortality in Patients With Diabetes Mellitus and COVID-19
Oct/23/2020
Statins reduce mortality in patients with COVID-19: an updated meta-analysis of 147 824 patients.
Aug/08/2021