Other substances

Sesamin

A lignan plant metabolite.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Natural product

Supporting references

Contradictory references

AI-suggested references

Clinical trials

General information

Sesamin on PubChem

Structure image - Sesamin

C1[C@H]2[C@H](CO[C@@H]2C3=CC4=C(C=C3)OCO4)[C@H](O1)C5=CC6=C(C=C5)OCO6

Supporting references

Link	Tested on	Impact factor	Notes	Publication date
An in-silico evaluation of dietary components for structural inhibition of SARS-Cov-2 main protease 3CLpro Small molecule In silico	in silico	3.31	Predicted to inhibit SARS-CoV-2 3C-like protease.	Aug/18/2020
Molecular modelling investigation for drugs and nutraceuticals against protease of SARS-CoV-2 3CLpro Small molecule In silico	in silico	2.08	Predicted to inhibit the SARS-CoV-2 3C-like protease.	Aug/18/2020

AI-suggested references

Link	Publication date
An in silico approach to target RNA-dependent RNA polymerase of COVID-19 with naturally occurring phytochemicals.	Apr/03/2021
Inhibition Potencies of Phytochemicals Derived from Sesame Against SARS-CoV-2 Main Protease: A Molecular Docking and Simulation Study	Apr/28/2021
Antiviral phytocompounds "ellagic acid" and "(+)-sesamin" of Bridelia retusa identified as potential inhibitors of SARS-CoV-2 3CL pro using extensive molecular docking, molecular dynamics simulation studies, binding free energy calculations, and bioactivi	May/10/2022
In silico study of natural compounds from sesame against COVID-19 by targeting Mpro, PLpro and RdRp	Jun/24/2021