Potential treatment - pre-clinical evidence
|Link||Tested on||Impact factor||Notes||Publication date|
Discovery of naturally occurring inhibitors against SARS-CoV-2 3CLpro from Ginkgo biloba leaves via large-scale screening
3CLpro Enzyme assay In vitro In silico
|in silico; in vitro enzyme assay||2.53||
Sciadopitysin inhibited SARS-CoV-2 3C-like protease with an IC50 of ca. 1.09 μM. It was also computationally modelled to bind a druggable site of the protease.
Plant-derived chemicals as potential inhibitors of SARS-CoV-2 main protease (6LU7), a virtual screening study