Sciadopitysin
A flavone.
COC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4=C(C=CC(=C4)C5=CC(=O)C6=C(C=C(C=C6O5)OC)O)OC
Supporting references
| Link | Tested on | Impact factor | Notes | Publication date |
|---|---|---|---|---|
|
Discovery of naturally occurring inhibitors against SARS-CoV-2 3CLpro from Ginkgo biloba leaves via large-scale screening
3CLpro Enzyme assay In vitro In silico |
in silico; in vitro enzyme assay | 2.53 | Sciadopitysin inhibited SARS-CoV-2 3C-like protease with an IC50 of ca. 1.09 μM. It was also computationally modelled to bind a druggable site of the protease. |
Apr/22/2021 |
AI-suggested references
| Link | Publication date |
|---|---|
|
Plant-derived chemicals as potential inhibitors of SARS-CoV-2 main protease (6LU7), a virtual screening study
|
Mar/23/2021 |
