S1-Fc vaccine

candidate vaccine

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Vaccine

Drug status

Experimental

Supporting references

Contradictory references

AI-suggested references

Clinical trials

CHO-expressed recombinant SARS-CoV-2 S1-Fc fusion protein

Link	Tested on	Impact factor	Notes	Publication date
Recombinant SARS-CoV-2 spike S1-Fc fusion protein induced high levels of neutralizing responses in nonhuman primates Spike protein	mice, rabbits, monkeys	3.14	CHO-expressed S1-Fc protein is very immunogenic in various animals and can rapidly induce strong antibody production. S1-Fc protein solicits strong neutralizing activities against live virus.	Jul/31/2020
A Targeted Vaccine against COVID-19: S1-Fc Vaccine Targeting the Antigen-Presenting Cell Compartment Elicits Protection against SARS-CoV-2 Infection Preprint	murine cells			Jun/30/2020