Other substances

RTAM-PAP1

A chimeric protein.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Experimental

1
 Supporting references
0
 Contradictory references
0
 AI-suggested references
0
 Clinical trials

General information

RTAM-PAP1 is a chimeric protein constructed by a fusion of genes encoding ribosome-inactivating proteins found in seeds of Ricinus communis and leaves of Phytolacca americana (Hassan et al., 2020).

 

Supporting references

Link Tested on Impact factor Notes Publication date
Novel Binding Mechanisms of Fusion Broad Range Anti-Infective Protein Ricin A Chain Mutant-Pokeweed Antiviral Protein 1 (RTAM-PAP1) against SARS-CoV-2 Key Proteins in Silico
Spike protein 3CLpro Protein factor In silico 		in silico; BALB/c mice (toxicity only) 3.53

Predicted to have a strong binding affinity to the SARS-CoV-2 spike protein (and RBD) and 3C-like protease. Does not elicit observable adverse effects in mice in doses up to 1 mg/kg.

 Sep/17/2020
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