Other substances

Racecadotril

An enkephalinase inhibitor.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Used to treat other disease

1
 Supporting references
0
 Contradictory references
0
 AI-suggested references
0
 Clinical trials

General information

Racecadotril is an enkephalinase inhibitor and used for treating acute diarrhea (Fu et al., 2020).

Racecadotril on DrugBank
Racecadotril on PubChem
Racecadotril on Wikipedia

 

Structure image - Racecadotril

CC(=O)SCC(CC1=CC=CC=C1)C(=O)NCC(=O)OCC2=CC=CC=C2

Supporting references

Link Tested on Impact factor Notes Publication date
Repurposing FDA-approved drugs for SARS-CoV-2 through an ELISA-based screening for the inhibition of RBD/ACE2 interaction
Small molecule In vitro 		in vitro binding assay; HEK 293T cells; Vero E6 cells; Calu-3 cells 10.16

Disrupted (mildly) ACE2-RBD (of SARS-CoV-2 spike protein) interaction in vitro in a dose-dependent manner.

 Nov/18/2020
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