Quercetagetin

A natural flavonoid.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Natural product

2
Supporting references
0
Contradictory references
1
AI-suggested references
0
Clinical trials

General information

Quercetagetin is a natural flavonoid antioxidant (Yang et al., 2011).

Quercetagetin on PubChem


Synonyms

6-Hydroxyquercetin

 

Structure image - Quercetagetin

C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C=C(C(=C3O)O)O)O)O)O


Supporting references

Link Tested on Impact factor Notes Publication date
A large-scale transcriptional study reveals inhibition of COVID-19 related cytokine storm by traditional chinese medicines
TCM Small molecule In silico
in silico 9.51

The drug was identified as a component of a Traditional Chinese Medicine herb which was discovered to suppress transcriptional responses within IL-6 and TNF-α signalling pathways in immune cells linked to cytokine storm. The compound was computationally predicted to bind to STAT3 protein.

Jan/12/2021
Scutellaria baicalensis extract and baicalein inhibit replication of SARS-CoV-2 and its 3C-like protease in vitro
Small molecule Enzyme assay In vitro In silico
in silico; in vitro enzyme assay; Vero cells; HEK293T cell lysates; SARS-CoV-2 isolate C-Tan-nCoV Wuhan strain 01 4.31

Inhibits SARS-CoV-2 3C-like protease in vitro with IC50 of 1.24 µM.

Jan/04/2021

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