Other substances

Protirelin

A tripeptide hormone analogue.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Experimental

1
 Supporting references
0
 Contradictory references
1
 AI-suggested references
0
 Clinical trials

General information

Protirelin is a synthetic analogue of thyrotropin-releasing hormone (TRH), which is released by the hypothalamus and stimulates the release of thyroid stimulating hormone and prolactin from the anterior pituitary (DrugBank).

Protirelin on PubChem
Protirelin on Wikipedia

 

Structure image - Protirelin

C1C[C@H](N(C1)C(=O)[C@H](CC2=CN=CN2)NC(=O)[C@@H]3CCC(=O)N3)C(=O)N

Supporting references

Link Tested on Impact factor Notes Publication date
Screening of Therapeutic Agents for COVID-19 Using Machine Learning and Ensemble Docking Studies
Screening 		in silico 6.71

Predicted to bind the SARS-CoV-2 spike protein or spike protein:ACE2 interface.

 Aug/05/2020

AI-suggested references

Link Publication date
Ligand and Structure-Based In Silico Determination of the Most Promising SARS-CoV-2 nsp16-nsp10 2'-o-Methyltransferase Complex Inhibitors among 3009 FDA Approved Drugs.
Mar/31/2022
Export (.csv)