Polymyxin B
A cyclic polypeptide antibiotic.
General information
Polymyxin B on PubChem
Marketed as
AEROSPORIN; METAMYXIN; POLOMYXIN B; POLY-RX; POLYFAX; POLYXX
CCC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](NC1=O)CCN)CC2=CC=CC=C2)CC(C)C)CCN)CCN)[C@@H](C)O
Supporting references
| Link | Tested on | Impact factor | Notes | Publication date |
|---|---|---|---|---|
|
In Silico Drug Repurposing for SARS-CoV-2 Main Proteinase and Spike Proteins
Spike protein 3CLpro In silico |
in silico | 4.07 | Predicted to bind the SARS-CoV-2 spike protein. |
Sep/07/2020 |
AI-suggested references
Clinical trials
| ID | Title | Status | Phase | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04352985 | Evaluating the Use of Polymyxin B Cartridge Hemoperfusion for Patients With Septic Shock and COVID 19 | No longer available | Jan/01/1970 | Jan/01/1970 | |
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