Other substances

Perospirone

A serotonin and dopamine receptor antagonist.

Phase of research

Potential treatment - theoretical effect

How it helps

Other treatment

Drug status

Used to treat other disease

1
 Supporting references
0
 Contradictory references
0
 AI-suggested references
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 Clinical trials

General information

Perospirone is an azapirone family second-generation antipsychotic registered for treatment acute and chronic schizophrenia and bipolar mania in Japan. It is a serotonin (2A) and dopamine (D2) receptor antagonist and a partial agonist of serotonin (1A) receptors (DrugBank).

Perospirone on PubChem
Perospirone on Wikipedia

Marketed as

LULLAN (Perospirone hydrochloride)

 

Structure image - Perospirone

C1CC[C@H]2[C@@H](C1)C(=O)N(C2=O)CCCCN3CCN(CC3)C4=NSC5=CC=CC=C54

Supporting references

Link Tested on Impact factor Notes Publication date
Glucocorticoids improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels
in silico 4.86

In silico screening of potential ACE2 agonists. Theoretical amelioration of ACE2 depletion by virus attachment.

 Jun/27/2020
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