Other substances

Penfluridol

A diphenylbutylpiperidine antipsychotic.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Used to treat other disease

1
 Supporting references
0
 Contradictory references
0
 AI-suggested references
0
 Clinical trials

General information

Penfluridol is an atypical antipsychotic drug used for the treatment of schizophrenia. It is long-acting and low-cost (Soares and Lima, 2006).

Penfluridol on DrugBank
Penfluridol on PubChem
Penfluridol on Wikipedia

Marketed as

LONGOPERIDOL; MICEFAL; SEMAP

 

Structure image - Penfluridol

C1CN(CCC1(C2=CC(=C(C=C2)Cl)C(F)(F)F)O)CCCC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F

Supporting references

Link Tested on Impact factor Notes Publication date
Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection
3CLpro PapainLpro Enzyme assay Animal model In vitro In silico 		in silico; in vitro enzyme assay; Vero E6 cells; golden Syrian hamsters; SARS-CoV-2 clinical isolate hCoV-19/Taiwan/4/2020 9.41

Inhibited SARS-CoV-2 infection in Vero E6 cells (selectivity index of ca. 5.4).

 Jan/15/2021
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