Other substances

Pectolinarin

A natural flavone glycoside.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Natural product

1
 Supporting references
0
 Contradictory references
3
 AI-suggested references
0
 Clinical trials

General information

Pectolinarin is a natural flavone glycoside with potential anti-inflammatory properties (Lim et al., 2008).

Pectolinarin on Wikipedia
Pectolinarin on PubMed

 

Structure image - Pectolinarin

C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=C(C(=C4C(=C3)OC(=CC4=O)C5=CC=C(C=C5)OC)O)OC)O)O)O)O)O)O

Supporting references

Link Tested on Impact factor Notes Publication date
Flavonoids with inhibitory activity against SARS-CoV-2 3CLpro
in vitro 4.67

In vitro screening of selected flavonoids for their SARS-CoV-2 3CLpro binding/inhibitory activity (using a synthetic peptide).

 Aug/04/2020

AI-suggested references

Link Publication date
Structural Bioinformatics Used to Predict the Protein Targets of Remdesivir and Flavones in SARS-CoV-2 Infection.
Oct/08/2021
Potential of Plant Bioactive Compounds as SARS-CoV-2 Main Protease (Mpro) and Spike (S) Glycoprotein Inhibitors: A Molecular Docking Study.
Dec/23/2020
Targeting COVID-19 (SARS-CoV-2) main protease through active phytocompounds of ayurvedic medicinal plants - Emblica officinalis (Amla), Phyllanthus niruri Linn. (Bhumi Amla) and Tinospora cordifolia (Giloy) - A molecular docking and simulation study.
Jul/24/2021
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