pCMVkan-S
An experimental COVID-19 DNA vaccine.
General information
pCMVkan-S is an experimental COVID-19 DNA vaccine, which carries human codon-optimized full-length SARS-CoV-2 Spike protein gene without ER-retention signal sequence. It induced potent humoral and cellular immune response in mice when administered in a three-dose regimen (Prompetchara et al., 2021).
Supporting references
| Link | Tested on | Impact factor | Notes | Publication date |
|---|---|---|---|---|
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DNA vaccine candidate encoding SARS-CoV-2 spike proteins elicited potent humoral and Th1 cell-mediated immune responses in mice
Spike protein DNA Animal model In vitro |
in vitro binding assay; Vero cells; ICR mice; SARS-CoV-2 isolate hCoV-19/Thailand/47/2020 | 2.74 | The vaccine carrying a full-length version of SARS-CoV-2 Spike protein elicited Spike-binding (IgG1/IgG2a-balanced) antibody response, neutralising antibody response, and potent T cell response in mice. |
Mar/22/2021 |
