Other substances

Panduratin A

A diarylheptanoid.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Natural product

1
 Supporting references
0
 Contradictory references
1
 AI-suggested references
0
 Clinical trials

General information

Panduratin A is a Boesenbergia rotunda extract component with anti-SARS-CoV-2 properties in vitro (Kanjanasirirat et al., 2020).

Panduratin A on PubChem

 

Structure image - Panduratin A

CC1=CC[C@H]([C@@H]([C@@H]1CC=C(C)C)C(=O)C2=C(C=C(C=C2O)OC)O)C3=CC=CC=C3

Supporting references

Link Tested on Impact factor Notes Publication date
High-content screening of Thai medicinal plants reveals Boesenbergia rotunda extract and its component Panduratin A as anti-SARS-CoV-2 agents
Small molecule In vitro Mixed substance 		Vero E6 cells; Calu-3 cells; HepG2, imHC, HK-2, SH-SY5Y, and Caco-2 cells (cytotoxicity only) 4.00

Inhibits SARS-CoV-2 infection both pre- and post-entry in vitro at non-cytotoxic levels.

 Nov/17/2020

AI-suggested references

Link Publication date
Leveraging knowledge of Asian herbal medicine and its active compounds as COVID-19 treatment and prevention
Nov/14/2020
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