Other substances

Paliperidone

Putative dopamine (D2), serotonin (5HT2A), adrenergic (alpha 1 and 2) and histaminergic receptor antagonist.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Used to treat other disease

1
 Supporting references
0
 Contradictory references
1
 AI-suggested references
0
 Clinical trials

General information

Paliperidone is an FDA approved drug for treatment of schizophrenia. Its mechanism of action is mostly unknown but it is possibly active as a dopamine (D2), serotonin (5HT2A), adrenergic (alpha 1 and 2) and histaminergic receptor antagonist (DrugBank).

Paliperidone on PubChem
Paliperidone on Wikipedia

Marketed as

PALIPERIDONE; INVEGA; XEPLION

 

Structure image - Paliperidone

CC1=C(C(=O)N2CCCC(C2=N1)O)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F

Supporting references

Link Tested on Impact factor Notes Publication date
In silico identification of widely used and well-tolerated drugs as potential SARS-CoV-2 3C-like protease and viral RNA-dependent RNA polymerase inhibitors for direct use in clinical trials
in silico 3.31 Aug/05/2020

AI-suggested references

Link Publication date
Targeting two potential sites of SARS-CoV-2 main protease through computational drug repurposing.
Mar/10/2022
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