P5A-1B8
A human monoclonal anti-RBD (SARS-CoV-2) antibody.
General information
P5A-1B8 is a human monoclonal IgG antibody identified in COVID-19 convalescent patient serum. It binds SARS-CoV-2 RBD and neutralizes the virus in vitro (Yan et al., 2021).
Supporting references
Link | Tested on | Impact factor | Notes | Publication date |
---|---|---|---|---|
Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies
Spike protein Cryo-EM Biophysical assay In vitro Antibody |
in vitro biophysical assay; cryo-EM; Huh7 cells; Vero E6 cells; (HIV) SARS-CoV-2 Spike pseudovirus; SARS-CoV-2 isolate Beta/Shenzhen/SZTH-003/2020 | 20.51 | The antibody bound SARS-CoV-2 Spike protein RBD and neutralized SARS-CoV-2 live virus and Spike pseudovirus in vitro with IC50s of 0.11 nM and 0.08 nM, respectively. |
Mar/17/2021 |