P2C-1F11

An anti-RBD (SARS-CoV-2 Spike) monoclonal antibody.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Experimental

1
Supporting references
0
Contradictory references
2
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Clinical trials

General information

P2C-1F11 is an RBD-specific (SARS-CoV-2 Spike) human monoclonal antibody capable of neutralizing the (pseudo)virus in vitro. It was identified in a memory B cell of a convalescent individual (Ju et al., 2020).

 


Supporting references

Link Tested on Impact factor Notes Publication date
Human neutralizing antibodies elicited by SARS-CoV-2 infection
Spike protein Crystallization Novel compound Biophysical assay Protein factor In vitro Antibody
patient sera; in vitro biophysical assay; Huh-7 cells; Vero E6 cells; (HIV-1) SARS-CoV-2 Spike-pseudotyped virus; SARS-CoV-2 strain Beta/Shenzhen/SZTH-003/2020, EPI_ISL_406594 49.96

The antibody bound RBD and neutralized SARS-CoV-2 live/pseudo-virus in vitro. 

May/26/2020

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