Other substances

Orientin

A bioactive flavonoid.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Natural product

1
 Supporting references
0
 Contradictory references
3
 AI-suggested references
0
 Clinical trials

General information

Orientin on PubChem

Synonyms

Lutexin; Luteolin-8-glucoside

 

Structure image - Orientin

C1=CC(=C(C=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O

Supporting references

Link Tested on Impact factor Notes Publication date
In silico validation of potent phytochemical orientin as inhibitor of SARS-CoV-2 spike and host cell receptor GRP78 binding
Spike protein Small molecule In silico 		in silico

Predicted to bind SARS-CoV-2 Spike protein at its interface with the host GRP-78 receptor.

 Jan/11/2021

AI-suggested references

Link Publication date
Computer Aided Drug Design Approach to Screen Phytoconstituents of Adhatoda vasica as Potential Inhibitors of SARS-CoV-2 Main Protease Enzyme
Feb/20/2022
In Silico Studies of Phytoconstituents from Piper longum and Ocimum sanctum as ACE2 and TMRSS2 Inhibitors: Strategies to Combat COVID-19
Mar/13/2022
Ethnomedicines of Indian origin for combating COVID-19 infection by hampering the viral replication: using structure-based drug discovery approach
Jun/23/2020
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