Omega-3 polyunsaturated fatty acids
Natural fatty acids involved in human physiological processes.
General information
Omega-3 polyunsaturated fatty acids responsible for multiple cellular functions. They are essential for multiple processes in the human body (e.g. proper function of nervous system, blood clotting, or glucose tolerance). Omega-3 polyunsaturated fatty acids are investigated for their anti-inflammatory and antioxidant properties (Gammone et al., 2019).
Omega-3 polyunsaturated fatty acids on DrugBank
Omega-3 polyunsaturated fatty acids on Wikipedia
Synonyms
Omega-3 fatty acids; ω-3 fatty acids; n3-PUFAs
Supporting references
| Link | Tested on | Impact factor | Notes | Publication date |
|---|---|---|---|---|
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The effect of omega-3 fatty acid supplementation on clinical and biochemical parameters of critically ill patients with COVID-19: a randomized clinical trial
Small molecule Critical severity Randomized controlled double-blind trial Mixed substance |
Critically ill COVID-19 patients | 4.12 | The 1-month survival rate was higher in the treatment group compared to the control. Positive effects on acidosis and renal parameters in critically ill COVID-19 patients were observed, as well. (No significant difference was observed in several other clinical parameters, however.) Sample size: 28 + 73 placebo (final analyses). Dosage: 1000 mg daily enterally (400 mg EPAs and 200 mg DHAs) for 14 days. |
Mar/29/2021 |
AI-suggested references
Clinical trials
| ID | Title | Status | Phase | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04647604 | Resolving Inflammatory Storm in COVID-19 Patients by Omega-3 Polyunsaturated Fatty Acids - | Completed | Phase 2 | Jun/23/2020 | Jul/07/2021 |
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