Neratinib

A HER-2 receptor tyrosine kinase inhibitor.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Used to treat other disease

1
Supporting references
0
Contradictory references
0
AI-suggested references
0
Clinical trials

General information

Neratinib on PubChem


Synonyms

HKI-272


Marketed as

NERLYNX

 

Structure image - Neratinib

CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)/C=C/CN(C)C


Supporting references

Link Tested on Impact factor Notes Publication date
Potential clinical drugs as covalent inhibitors of the priming proteases of the spike protein of SARS-CoV-2
TMPRSS2 Cathepsin B Cathepsin L Small molecule In silico
in silico 6.02

Predicted to inhibit the host cathepsin B and L proteases and thereby inhibit the SAS-CoV-2 entry.

Aug/26/2020