Other substances

Neohesperidin

A flavanone glycoside.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Natural product

2
 Supporting references
0
 Contradictory references
1
 AI-suggested references
0
 Clinical trials

General information

A natural compound (a flavanone glycoside) isolated from citrus fruits (Rouseff et al., 1987).

Neohesperidin on PubChem
Neohesperidin on Wikipedia

Synonyms

(S)-7-(((2-O-6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one

 

Structure image - Neohesperidin

C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=CC(=C4C(=O)C[C@H](OC4=C3)C5=CC(=C(C=C5)OC)O)O)CO)O)O)O)O)O

Supporting references

Link Tested on Impact factor Notes Publication date
Identification of potential anti-TMPRSS2 natural products through homology modelling, virtual screening and molecular dynamics simulation studies
in silico 3.31

In silico TMPRSS2 inhibitors screening.

 Aug/03/2020
Repurposing FDA-approved phytomedicines, natural products, antivirals and cell protectives against SARS-CoV-2 (COVID-19) RNA-dependent RNA polymerase
RdRpol Small molecule In silico 		in silico 2.38

Predicted to bind the SARS-CoV-2 RNA-dependent RNA polymerase.

 Nov/30/2020

AI-suggested references

Link Publication date
Strawberry and Ginger Silver Nanoparticles as Potential Inhibitors for SARS-CoV-2 Assisted by In Silico Modeling and Metabolic Profiling.
Jul/06/2021
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