Other substances

Naphthazarin

A 1,4-naphthoquinone.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Natural product

1
 Supporting references
0
 Contradictory references
0
 AI-suggested references
0
 Clinical trials

General information

Naphthazarin is a 1,4-naphthoquinone plant metabolite. It has antibacterial, acaricide, antineoplastic, and pro-apoptotic properties (ChEBI).

Naphthazarin on PubChem
Naphthazarin on Wikipedia

Synonyms

5,8-Dihydroxy-1,4-naphthoquinone

 

Structure image - Naphthazarin

C1=CC(=C2C(=O)C=CC(=O)C2=C1O)O


 

Supporting references

Link Tested on Impact factor Notes Publication date
Identification of Vitamin K3 and its analogues as covalent inhibitors of SARS-CoV-2 3CLpro
3CLpro Small molecule Enzyme assay In vitro In silico 		in silico; in vitro enzyme assay 5.16

The compound inhibited SARS-CoV-2 3C-like protease with an IC50 of ca. 0.49 μM in vitro.

 Apr/24/2021
Export (.csv)