Other substances

Naldemedine

An opioid receptor antagonist.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Used to treat other disease

1
 Supporting references
0
 Contradictory references
3
 AI-suggested references
0
 Clinical trials

General information

Naldemedine on PubChem

Marketed as

SYMPROIC

 

Structure image - Naldemedine

CC(C)(C1=NC(=NO1)C2=CC=CC=C2)NC(=O)C3=C([C@H]4[C@@]56CCN([C@@H]([C@@]5(C3)O)CC7=C6C(=C(C=C7)O)O4)CC8CC8)O

Supporting references

Link Tested on Impact factor Notes Publication date
Identification and characterization of novel RdRp and Nsp15 inhibitors for SARS-COV2 using computational approach
RdRpol nsp15 Small molecule In silico 		in silico 3.22

Predicted to inhibit the SARS-CoV-2 RNA-dependent RNA polymerase and nsp15 protein.

 Nov/05/2020

AI-suggested references

Link Publication date
Antiviral drug design based on the opening mechanism of spike glycoprotein in SARS-CoV-2.
May/15/2021
Repositioning of Ligands That Target the Spike Glycoprotein as Potential Drugs for SARS-CoV-2 in an In Silico Study
Nov/08/2021
Computational estimation of potential inhibitors from known drugs against the main protease of SARS-CoV-2
May/12/2021
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