Other substances

N-(4-[(2E)-3-(4-ethoxyphenyl)-1-(phenyl)prop-2-en-1-one]) acetamide

A chalconid.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Experimental

1
 Supporting references
0
 Contradictory references
1
 AI-suggested references
0
 Clinical trials

General information

N-(4-[(2E)-3-(4-ethoxyphenyl)-1-(phenyl)prop-2-en-1-one]) acetamide is a 4'-acetamidochalcone derivative (Almeida-Neto et al., 2020).

Synonyms

PAAPE

 

Structure image - N-(4-[(2E)-3-(4-ethoxyphenyl)-1-(phenyl)prop-2-en-1-one]) acetamide

CCOC1=CC=C(\C=C\C(=O)C2=CC=C(NC(C)=O)C=C2)C=C1

Supporting references

Link Tested on Impact factor Notes Publication date
In silico study of the potential interactions of 4′-acetamidechalcones with protein targets in SARS-CoV-2
Spike protein 3CLpro ACE2 nsp16 nsp10 Small molecule In silico 		in silico 2.99

Predicted to interact with the SARS-CoV-2 Spike protein.

 Dec/26/2020

AI-suggested references

Link Publication date
In silico study of the potential interactions of 4'-acetamidechalcones with protein targets in SARS-CoV-2.
Dec/26/2020
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