N-({(2S)-1-[(3R)-3-Amino-4-(2-fluorophenyl)butanoyl]pyrrolidin-2-YL}methyl)benzamide

An inhibitor of dipeptidyl peptidase 4.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Experimental

1
Supporting references
0
Contradictory references
0
AI-suggested references
0
Clinical trials

General information

N-({(2S)-1-[(3R)-3-Amino-4-(2-fluorophenyl)butanoyl]pyrrolidin-2-YL}methyl)benzamide on PubChem


Synonyms

DB07779

 

Structure image - N-({(2S)-1-[(3R)-3-Amino-4-(2-fluorophenyl)butanoyl]pyrrolidin-2-YL}methyl)benzamide

C1C[C@H](N(C1)C(=O)C[C@@H](CC2=CC=CC=C2F)N)CNC(=O)C3=CC=CC=C3


Supporting references

Link Tested on Impact factor Notes Publication date
Structural Insights into the Binding Modes of Viral RNA-Dependent RNA Polymerases Using a Function-Site Interaction Fingerprint Method for RNA Virus Drug Discovery
RdRpol Small molecule In silico
in silico 4.07

Predicted to inhibit the SARS-CoV-2 RNA-dependent RNA polymerase via subpocket 1 binding.

Sep/18/2020