N-[(2R)-2-(1H-Indol-3-yl)-2-thiophen-2-ylethyl]-2-oxo-1H-quinoline-4-carboxamide

A putative SARS-CoV-2 3C-like protease inhibitor.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Experimental

1
Supporting references
0
Contradictory references
0
AI-suggested references
0
Clinical trials

General information

N-[(2R)-2-(1H-Indol-3-yl)-2-thiophen-2-ylethyl]-2-oxo-1H-quinoline-4-carboxamide on PubChem


Synonyms

ZINC32960814

 

Structure image - N-[(2R)-2-(1H-Indol-3-yl)-2-thiophen-2-ylethyl]-2-oxo-1H-quinoline-4-carboxamide

C1=CC=C2C(=C1)C(=CC(=O)N2)C(=O)NC[C@H](C3=CC=CS3)C4=CNC5=CC=CC=C54


Supporting references

Link Tested on Impact factor Notes Publication date
Identification of Potential Inhibitors of 3CL Protease of SARS-CoV-2 From ZINC Database by Molecular Docking-Based Virtual Screening
3CLpro Small molecule In silico
in silico 4.19

Predicted to inhibit SARS-CoV-2 3C-like protease.

Dec/17/2020