Other substances

N-[(1R)-2-[4-(1-Methylpiperidin-4-yl)piperazin-1-yl]-2-oxo-1-phenylethyl]-1H-indole-6-carboxamide

A coagulation factor X inhibitor.

Phase of research

Approved for COVID-19 treatment (China, India, Russia)

How it helps

Antiviral

Drug status

Experimental

1
 Supporting references
0
 Contradictory references
0
 AI-suggested references
0
 Clinical trials

General information

N-[(1R)-2-[4-(1-Methylpiperidin-4-yl)piperazin-1-yl]-2-oxo-1-phenylethyl]-1H-indole-6-carboxamide on PubChem

Synonyms

LY-517717

 

Structure image - N-[(1R)-2-[4-(1-Methylpiperidin-4-yl)piperazin-1-yl]-2-oxo-1-phenylethyl]-1H-indole-6-carboxamide

CN1CCC(CC1)N2CCN(CC2)C(=O)[C@@H](C3=CC=CC=C3)NC(=O)C4=CC5=C(C=C4)C=CN5

Supporting references

Link Tested on Impact factor Notes Publication date
Structural Insights into the Binding Modes of Viral RNA-Dependent RNA Polymerases Using a Function-Site Interaction Fingerprint Method for RNA Virus Drug Discovery
RdRpol Small molecule In silico 		in silico 4.07

Predicted to inhibit the SARS-CoV-2 RNA-dependent RNA polymerase via subpocket 2 binding.

 Sep/18/2020
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