Other substances

MXB-4

A peptoid.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Experimental

1
 Supporting references
0
 Contradictory references
0
 AI-suggested references
0
 Clinical trials

General information

MXB-4 is a peptoid – a stable peptidomimetic. It displayed anti-SARS-CoV-2 activity in vitro, possibly via interaction with the viral envelope prior to cell entry (Diamond et al., 2021).

 

Supporting references

Link Tested on Impact factor Notes Publication date
Potent Antiviral Activity against HSV-1 and SARS-CoV-2 by Antimicrobial Peptoids
Cryo-EM Peptide In vitro 		cryo-EM; Vero E6 cells; SARS-CoV-2 strain USA-WA1/2021 4.29

Inhibited SARS-CoV-2 infection in Vero E6 cells with an IC50 of 20 μg/ml if incubated with the virus prior to cell infection.

 Mar/31/2021
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