Other substances

MRT5500

An experimental COVID-19 mRNA-based vaccine.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Vaccine

Drug status

Experimental

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 Contradictory references
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 AI-suggested references
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 Clinical trials

General information

MRT5500 is an experimental COVID-19 mRNA vaccine. The mRNA encodes a pre-fusion-stabilized SARS-CoV-2 Spike protein without a Furin cleavage site and an endoplasmic reticulum retention signal. The vaccine mRNA is delivered in lipid nanoparticles. It displayed immunogenicity and efficacy in animal model studies (Kalnin et al., 2021).

 

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