MI-1851

synthetic furin inhibitor

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Experimental

Supporting references

Contradictory references

AI-suggested references

Clinical trials

Link	Tested on	Impact factor	Notes	Publication date
TMPRSS2 and furin are both essential for proteolytic activation and spread of SARS-CoV-2 in human airway epithelial cells and provide promising drug targets	Calu-3 human airway epithelial cells			Apr/15/2020

Link	Publication date
In vitro characterization of the furin inhibitor MI-1851: Albumin binding, interaction with cytochrome P450 enzymes and cytotoxicity.	May/17/2022
TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells	Jul/23/2020