Maduramicin
A polyether ionophore antibiotic.
General information
Maduramicin is an o-glycosyl antiprotozoal compound used in veterinary medicine (DrugBank).
Maduramicin (ammonium) on PubChem
Maduramicin on Wikipedia
Synonyms
Maduramicin ammonium; Maduramycin
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Supporting references
| Link | Tested on | Impact factor | Notes | Publication date |
|---|---|---|---|---|
|
Ionophore antibiotic X-206 is a potent inhibitor of SARS-CoV-2 infection in vitro
Small molecule In vitro |
Vero E6 cells; Vero E6-hTMPRSS2 cells; Calu-3 cells | 4.10 | Inhibited SARS-CoV-2 in cell culture with high selectivity (the ratio between IC50 and EC50). |
Nov/25/2020 |
|
Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection
3CLpro PapainLpro Enzyme assay Animal model In vitro In silico |
in silico; in vitro enzyme assay; Vero E6 cells; golden Syrian hamsters; SARS-CoV-2 clinical isolate hCoV-19/Taiwan/4/2020 | 9.41 | Inhibited SARS-CoV-2 infection in Vero E6 cells (selectivity index of ca. 4.8 - although described as "no selectivity" by the authors in the text). |
Jan/15/2021 |
