mAb 2-43

An anti-Spike (SARS-CoV-2) monoclonal antibody.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Experimental

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Supporting references
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Contradictory references
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AI-suggested references
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Clinical trials

General information

mAb 2-43 was identified in a convalescent COVID-19 patient memory B cell screening. It neutralized SARS-CoV-2 live virus with an IC50 of 0.003 μg/mL in vitro (Liu et al., 2020). The antibody’s tertiary structure and interaction with Spike RBD has been described by Rapp et al. (2021).