Other substances

Liquiritin

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Natural product

Supporting references

Contradictory references

AI-suggested references

Clinical trials

General information

Liquiritin is one of the main flavonoids in Glycyrrhiza uralensis, which acts as an antioxidant and has antidepressant, neuroprotective, anti-inflammatory and therapeutic effects on heart system diseases. Liquiritin is abundant in licorice tablet (~0.2% by mass), a traditional Chinese medicine.

Supporting references

Link	Tested on	Impact factor	Notes	Publication date
An artificial intelligence system reveals liquiritin inhibits SARS-CoV-2 by mimicking type I interferon Preprint	VERO E6 cell cultures			May/02/2020

AI-suggested references

Link	Publication date
Potential Leads from Liquorice Against SARS-CoV-2 Main Protease using Molecular Docking Simulation Studies.	Aug/19/2020
Traditional Uses, Pharmacological Effects, and Molecular Mechanisms of Licorice in Potential Therapy of COVID-19	Jan/01/2021
Pharmacokinetics-based identification of pseudoaldosterogenic compounds originating from Glycyrrhiza uralensis roots (Gancao) after dosing LianhuaQingwen capsule	Apr/30/2021
Biologically guided isolation and ADMET profile of new factor Xa inhibitors from Glycyrrhiza glabra roots using in vitro and in silico approaches.	Mar/09/2021
Glycan Epitopes and Potential Glycoside Antagonists of DC-SIGN Involved in COVID-19: In Silico Study.	Oct/27/2021
In silico analysis of the potential mechanism of a preventive Chinese medicine formula on coronavirus disease 2019.	Apr/05/2021

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