Other substances

Limonin

A hexacyclic triterpenoid.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Natural product

1
 Supporting references
0
 Contradictory references
4
 AI-suggested references
0
 Clinical trials

General information

Limonin on PubChem
Limonin on Wikipedia

 

Structure image - Limonin

C[C@@]12CC[C@H]3[C@]([C@@]14[C@H](O4)C(=O)O[C@H]2C5=COC=C5)(C(=O)C[C@@H]6[C@@]37COC(=O)C[C@@H]7OC6(C)C)C

Supporting references

Link Tested on Impact factor Notes Publication date
In silico virtual screening, characterization, docking and molecular dynamics studies of crucial SARS-CoV-2 proteins
RdRpol ACE2 Small molecule In silico Screening 		in silico 3.31

Predicted to bind human ACE2 receptor for SARS-CoV-2 entry.

 Aug/07/2020

AI-suggested references

Link Publication date
In silico ADMET and molecular docking study on searching potential inhibitors from limonoids and triterpenoids for COVID-19.
Jul/28/2020
Virtual screening by targeting proteolytic sites of furin and TMPRSS2 to propose potential compounds obstructing the entry of SARS-CoV-2 virus into human host cells.
Apr/12/2021
Computational studies on the interaction of SARS-CoV-2 Omicron SGp RBD with human receptor ACE2, limonin and glycyrrhizic acid
Mar/01/2022
Exploring the therapeutic nature of limonoids and triterpenoids against SARS-CoV-2 by targeting nsp13, nsp14, and nsp15 through molecular docking and dynamic simulations
Nov/05/2021
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