Kaempferol
A tetrahydroxyflavone.
General information
Kaempferol is a tetrahydroxyflavone. Due to its antioxidant properties it is considered for cancer treatment. Kaempferol also displays antibacterial activity (ChEBI).
Kaempferol on DrugBank
Kaempferol on PubChem
Kaempferol on Wikipedia
Synonyms
Kaempherol; Kempferol; Robigenin
C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O
Supporting references
Link | Tested on | Impact factor | Notes | Publication date |
---|---|---|---|---|
An in-silico evaluation of different bioactive molecules of tea for their inhibition potency against non structural protein-15 of SARS-CoV-2
nsp15 Small molecule In silico |
in silico | 6.31 | Predicted to inhibit the SARS-CoV-2 endoribonuclease (nsp15). |
Dec/28/2020 |
In silico and in vitro evaluation of kaempferol as a potential inhibitor of the SARS‐CoV‐2 main protease (3CLpro)
3CLpro Small molecule In vitro In silico |
in silico; Vero E6 cells; SARS‐CoV‐2 live virus (GeneBank MT123290.1) | 4.09 | The compound was computationally predicted to bind the SARS-CoV-2 3C-like protease and inhibited SARS-CoV-2-induced cytopathic effect in Vero E6 cells with an estimated IC50 of ca. 34.5 μM. |
Jan/15/2021 |
A network pharmacology based approach for predicting active ingredients and potential mechanism of Lianhuaqingwen capsule in treating COVID-19
3CLpro Small molecule In silico |
in silico | 2.52 | Predicted to bind SARS-CoV-2 3C-like protease. |
Feb/24/2021 |