Ivacaftor

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Used to treat other disease

2
Supporting references
0
Contradictory references
2
AI-suggested references
0
Clinical trials

 


Supporting references

Link Tested on Impact factor Notes Publication date
Comparative analysis of antiviral efficacy of FDA-approved drugs against SARS-CoV-2 in human lung cells: Nafamostat is the most potent antiviral drug candidate
Preprint
Calu-3 human airway epithelial cells

comparable IC50 value between Calu-3 and VERO E6 cells

May/12/2020
Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection
3CLpro PapainLpro Enzyme assay Animal model In vitro In silico
in silico; in vitro enzyme assay; Vero E6 cells; golden Syrian hamsters; SARS-CoV-2 clinical isolate hCoV-19/Taiwan/4/2020 9.41

Inhibited SARS-CoV-2 infection in Vero E6 cells (selectivity index of ca. 3.5).

Jan/15/2021

AI-suggested references