Indole-3-carbinol

A natural indolyl alcohol.

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Natural product

Supporting references

Contradictory references

AI-suggested references

Clinical trials

Indole-3-carbinol is an indolyl alcohol with potential antineoplastic properties (ChEBI).

Indole-3-carbinol on DrugBank
Indole-3-carbinol on PubChem
Indole-3-carbinol on Wikipedia

I3C; 3-Indolemethanol

Link	Tested on	Impact factor	Notes	Publication date
Inhibition of HECT E3 ligases as potential therapy for COVID-19 Small molecule In vitro	Vero E6 cells; SARS-CoV-2 isolate 2019-nCoV/Italy-INMI1	6.30	The compound displayed anti-SARS-CoV-2 activity in Vero E6 cells, which might be linked to its activity as an inhibitor of HECT-E3 ligases.	Mar/24/2021