Other substances

Hinokiflavone

A cytotoxic biflavonoid.

Phase of research

Potential treatment - theoretical effect

How it helps

Antiviral

Drug status

Natural product

Supporting references

Contradictory references

AI-suggested references

Clinical trials

General information

Hinokiflavone on PubChem

Structure image - Hinokiflavone

C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C(=C3O)OC4=CC=C(C=C4)C5=CC(=O)C6=C(C=C(C=C6O5)O)O)O)O

Supporting references

Link	Tested on	Impact factor	Notes	Publication date
Exploring the efficacy of naturally occurring biflavone based antioxidants towards the inhibition of the SARS-CoV-2 spike glycoprotein mediated membrane fusion Spike protein ACE2 Small molecule In silico	in silico	2.82	Predicted to inhibit the SARS-CoV-2 Spike protein's interaction with the host ACE2 receptor.	Feb/04/2021

AI-suggested references

Link	Publication date
Natural biflavonoids as potential therapeutic agents against microbial diseases.	Mar/20/2021
Computational assessment of select antiviral phytochemicals as potential SARS-Cov-2 main protease inhibitors: molecular dynamics guided ensemble docking and extended molecular dynamics.	Jul/19/2021
Camphor, Artemisinin and Sumac Phytochemicals as inhibitors against COVID-19: Computational approach.	Aug/11/2021
In vitro testing and computational analysis of specific phytochemicals with antiviral activities considering their possible applications against COVID-19	Feb/10/2022