Hemin
A porphyrin.
General information
Hemin is a porphyrin containing a ferric ion. It is used for the management of porphyria attacks (DrugBank).
Hemin on PubChem
Hemin on Wikipedia
Synonyms
Chlorohemin; Hemin chloride; Protoferriheme; Ferriheme; Haemin; Ferriprotoporphyrin IX; Panhematin; Protohemin; Ferriprotoporphyrin; Chloroprotohemin; Hemin IX; Hemine; Hamin
Marketed as
PANHEMATIN
CC1=C(C2=CC3=C(C(=C([N-]3)C=C4C(=C(C(=N4)C=C5C(=C(C(=N5)C=C1[N-]2)C)C=C)C)C=C)C)CCC(=O)O)CCC(=O)O.[Cl-].[Fe+3]
Supporting references
| Link | Tested on | Impact factor | Notes | Publication date |
|---|---|---|---|---|
|
A drug repurposing screen identifies hepatitis C antivirals as inhibitors of the SARS-CoV2 main protease
3CLpro Enzyme assay In vitro In silico Screening |
in silico; in vitro enzyme assay | 2.74 | Inhibited the SARS-CoV-2 3C-like protease in vitro with IC50 of ca. 9.68 μM. |
Feb/01/2021 |
