Other substances

Ginkgolic acid C17:1

Phase of research

Potential treatment - pre-clinical evidence

How it helps

Antiviral

Drug status

Natural product

1
 Supporting references
0
 Contradictory references
0
 AI-suggested references
0
 Clinical trials

General information

Ginkgolic acid C17:1 on PubChem

Synonyms

2-(10-Heptadecenyl)-6-hydroxybenzoic acid

 

Structure image - Ginkgolic acid C17:1

CCCCCC/C=C\CCCCCCCCCC1=C(C(=CC=C1)O)C(=O)O


 

Supporting references

Link Tested on Impact factor Notes Publication date
Discovery of naturally occurring inhibitors against SARS-CoV-2 3CLpro from Ginkgo biloba leaves via large-scale screening
3CLpro Enzyme assay In vitro In silico 		in silico; in vitro enzyme assay 2.53

Gingkolic acid C17:1 inhibited SARS-CoV-2 3C-like protease with an IC50 of ca. 1.19 μM. It was also computationally modelled to bind a druggable site of the protease.

 Apr/22/2021
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